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smdl
I love Gary too..on a plate!
Member since 5/06 32461 total posts
Name:
me
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Genetic counceling Q
Is there any data I can find on the probability of having another child with austism/PDD? I can't seem to find anything other that there is "no rhyme or reason".
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Posted 4/29/09 4:42 PM  |
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Re: Genetic counceling Q
I'm not 100% sure but I think it's a 1 in 9 chance.
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| Posted 4/29/09 4:43 PM |
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EmmaNick
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Member since 12/06 16001 total posts
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Re: Genetic counceling Q
I think you would have to know the gender of your next child to determine the probability, since boys are four times more likely than girls to have autism.
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| Posted 4/29/09 10:12 PM |
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tran92
LIF Adolescent
Member since 2/08 732 total posts
Name:
Amy
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Re: Genetic counceling Q
my friend i think when through the genetic counseling. her older one is most likely aspergers. they told her she had a 10% chance of having another child on the spectrum. but there were other instances of autism in the extended family. (not sure if that changed the numbers) but also keep in mind the incidence of autism in girls is much lower than boys. (she had a girl the second time around and her DD is fine btw)
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| Posted 4/30/09 12:09 AM |
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McLovin
LIF Infant
Member since 3/09 119 total posts
Name:
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Re: Genetic counceling Q
Like the PPs said, the chances of having another child with autism depend on several factors:
1. the sex of the child
2. if/how many other relatives are affected
3. environmental factors that may be out of your control
(just to name a few)
Since one particular gene for autism hasn't been identified yet, it is hard to determine the inheritance pattern for a certain child. There have been several genes identified that may play a role, but chances are that environment also plays a role as well, making it hard to figure out your chances. In general, the chances of having another child on the autism spectrum will be from 2-10%. These numbers are based on studies looking at identical and non-identical twins with and without autism. The papers are kind of sciency, but if you really want to read them, I can point you in the right direction (i have a phd in genetics)
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| Posted 4/30/09 5:55 PM |
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GioiaMia
Let's Go Rangers!
Member since 1/07 14818 total posts
Name:
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Re: Genetic counceling Q
Posted by McLovin
Like the PPs said, the chances of having another child with autism depend on several factors:
1. the sex of the child
2. if/how many other relatives are affected
3. environmental factors that may be out of your control
(just to name a few)
Since one particular gene for autism hasn't been identified yet, it is hard to determine the inheritance pattern for a certain child. There have been several genes identified that may play a role, but chances are that environment also plays a role as well, making it hard to figure out your chances. In general, the chances of having another child on the autism spectrum will be from 2-10%. These numbers are based on studies looking at identical and non-identical twins with and without autism. The papers are kind of sciency, but if you really want to read them, I can point you in the right direction (i have a phd in genetics)
If you have any information on the probability of a first cousin being on the spectrum - please let me know - thanks!
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| Posted 5/1/09 7:41 AM |
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McLovin
LIF Infant
Member since 3/09 119 total posts
Name:
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Re: Genetic counceling Q
Posted by Tilde
If you have any information on the probability of a first cousin being on the spectrum - please let me know - thanks!
So would your child have a first cousin with autism? If thats the case, then the chances are pretty low, although they are higher than if you didn't have any family members with autism. There is a paper in the American Journal of Medical Genetics from 2005 that looked at autism in family members and found that while it does cluster in families, it is much more likely that your autistic niece/nephew will have an autistic sibling (and an autistic child of their own down the road) than for you and your husband to have a child with autism. They state the chances at around 1:1000-1:4000.
But again, this research is all very new and still ongoing, so nothing is definite. I hope that helps!
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| Posted 5/1/09 2:49 PM |
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GioiaMia
Let's Go Rangers!
Member since 1/07 14818 total posts
Name:
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Re: Genetic counceling Q
Posted by McLovin
Posted by Tilde
If you have any information on the probability of a first cousin being on the spectrum - please let me know - thanks!
So would your child have a first cousin with autism? If thats the case, then the chances are pretty low, although they are higher than if you didn't have any family members with autism. There is a paper in the American Journal of Medical Genetics from 2005 that looked at autism in family members and found that while it does cluster in families, it is much more likely that your autistic niece/nephew will have an autistic sibling (and an autistic child of their own down the road) than for you and your husband to have a child with autism. They state the chances at around 1:1000-1:4000.
But again, this research is all very new and still ongoing, so nothing is definite. I hope that helps!
Thanks - yeah that is what I was asking. 
My nephew has autism and his sister has Asperger's so I guess they fit the statistics! So far, none of their cousins show any of the signs.
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| Posted 5/2/09 9:58 PM |
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cjik
Welcome 2010!
Member since 2/06 8879 total posts
Name:
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Re: Genetic counceling Q
I don't know myself, but DH and I saw a genetic counselor before DS was born. My OB-GYN recommended her, so you might want to see someone if you are concerned.
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| Posted 5/4/09 1:28 PM |
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