She welcomed son Henry in June and her twins, Hazel and Phinnaeus, turn 3 later this month.

And that's quite enough baby action for Julia Roberts.

She hints in December's Vanity Fair that she and her husband, cameraman Danny Moder, may be done having kids.

“At this point I’m having so much fun with [her three children]," Roberts — who turned 40 on October 28 — says. "You only have so much energy and you want to put so much energy into each child. I wouldn’t know how to have five kids. And they’re really a good trio, these three.”

But the mom isn't putting her career on the back burner (she returns to the big screen in the December drama Charlie Wilson's War).

Roberts — who has starred opposite A-listers including American Gangster box office champ Denzel Washington — admits she still longs to work with one actor: Johnny Depp.

“I think he’s so interesting, and I think we look alike in a funny way," he said. "Johnny Depp and I will play brother and sister in something.”