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2 covid-19 vaccines on the horizon
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GoldenRod
10 years on LIF!
Member since 11/06 26792 total posts
Name:
Shawn
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2 covid-19 vaccines on the horizon
https://www.cnn.com/2020/11/16/health/moderna-vaccine-results-coronavirus/index.html
The Moderna vaccine is 94.5% effective against coronavirus, according to early data released Monday by the company, making it the second vaccine in the United States to have a stunningly high success rate.
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Vaccinations could begin in the second half of December, Fauci said. Vaccinations are expected to begin with high-risk groups and to be available for the rest of the population next spring.
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Last week, Pfizer announced that early data show its vaccine is more than 90% effective against the disease.
In Moderna's trial, 15,000 study participants were given a placebo, which is a shot of saline that has no effect. Over several months, 90 of them developed Covid-19, with 11 developing severe forms of the disease.
Another 15,000 participants were given the vaccine, and only five of them developed Covid-19. None of the five became severely ill.
The company says its vaccine did not have any serious side effects. A small percentage of those who received it experienced symptoms such as body aches and headaches.
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"I think that everybody else will start to get vaccinated towards the end of April," Fauci said. "And that will go into May, June, July. It will take a couple of months to do."
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Pfizer's and Moderna's vaccines have similar results because they use the same technique to activate the body's immune system.
The vaccines deliver messenger RNA, or mRNA, which is a genetic recipe for making the spikes that sit atop the coronavirus. Once injected, the body's immune system makes antibodies to the spikes. If a vaccinated person is later exposed to the coronavirus, those antibodies should stand at the ready to attack the virus.
Research on mRNA began many years before the current pandemic.
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While the two vaccines appear to have very similar safety and efficacy profiles, Moderna's vaccine has a significant practical advantage over Pfizer's.
Pfizer's vaccine has to be kept at minus 75 degrees Celsius. No other vaccine in the US needs to be kept that cold, and doctors' offices and pharmacies do not have freezers that go that low.
Moderna's vaccine can be kept at minus 20 degrees Celsius. Other vaccines, such as the one against chickenpox, need to be kept at that temperature.
That means Moderna's vaccine can be kept in "a readily available freezer that is available in most doctors' offices and pharmacies," Zacks said. "We leverage infrastructure that already exists for other marketed vaccines."
Another advantage of Moderna's vaccine is that it can be kept for 30 days in the refrigerator, the company announced Monday. Pfizer's vaccine can last only five days in the refrigerator.
This looks very promising. Hopefully the antibodies last longer than a few months. It sounds like this method is different than natural antibodies, so it may.
It will be a rough winter, but at least with a light at the end of the tunnel, a quarantine with an "end date" is easier to tolerate.
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Posted 11/16/20 7:39 PM  |
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seaside
LIF Adult
Member since 6/08 3101 total posts
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Re: 2 covid-19 vaccines on the horizon
Can't wait. I would much rather deal with dead or synthesized scary virus than live scary virus, and as long as the educated people I know who have a basis upon which to make an informed decision (I don't) opt in for themselves and their families, we are in.
My "reserach" will consist of talking with actual people educated in chemistry, physiology, and diseases and listening to what famous educated people say in the media--and seeing what they choose for themselves. No youtube vdeos or sourceless internet memes or hearsay.
Like so many have said, this virus isn't going to magically disappear. We will have to engage with it one way or another.
Message edited 11/16/2020 11:22:41 PM.
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| Posted 11/16/20 11:22 PM |
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GoldenRod
10 years on LIF!
Member since 11/06 26792 total posts
Name:
Shawn
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Re: 2 covid-19 vaccines on the horizon
The fact that two separate companies came up with a similar answer, with similar results, speaks a lot for the vaccine.
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| Posted 11/17/20 3:28 AM |
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MrsA1012
love my little girl !
Member since 9/10 5777 total posts
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Me
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2 covid-19 vaccines on the horizon
no thanks !
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| Posted 11/18/20 12:27 PM |
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DancinBarefoot
06ers Rock!!
Member since 1/07 9534 total posts
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The One My Mother Gave Me ;-)
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Re: 2 covid-19 vaccines on the horizon
Posted by GoldenRod
The fact that two separate companies came up with a similar answer, with similar results, speaks a lot for the vaccine.
I agree with this, but I can't help but be very concerned. First, just by the speed of all of this. It's way faster than any other vaccine has potentially come to market.
But also, 90%+ efficacy??? Really?? Flu vaccine is @ 60%. Two doses of MMR is @ 88% at protecting from mumps. Varicella is also in the 85-90% range. How is it that a brand new vaccine, for a novel virus, has such a high rate at protecting against contracting this illness?? Especially when all the studies and research have shown that contracting the illness doesn't appear to give sustained immunity as the antibodies diminish over time. Not to mention the fact that MMR and varicella have been distributed for more than 20 years.
I'm skeptical. Also, Pfizer's vaccine needs to be stored at temperatures so low nobody has adequate equipment, and Moderna's just needs regular refrigeration. What's that about?
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| Posted 11/18/20 1:00 PM |
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Diane
Hope is Contagious....catch it
Member since 5/05 30683 total posts
Name:
D
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Re: 2 covid-19 vaccines on the horizon
Posted by DancinBarefoot
Posted by GoldenRod
The fact that two separate companies came up with a similar answer, with similar results, speaks a lot for the vaccine.
I agree with this, but I can't help but be very concerned. First, just by the speed of all of this. It's way faster than any other vaccine has potentially come to market.
But also, 90%+ efficacy??? Really?? Flu vaccine is @ 60%. Two doses of MMR is @ 88% at protecting from mumps. Varicella is also in the 85-90% range. How is it that a brand new vaccine, for a novel virus, has such a high rate at protecting against contracting this illness?? Especially when all the studies and research have shown that contracting the illness doesn't appear to give sustained immunity as the antibodies diminish over time. Not to mention the fact that MMR and varicella have been distributed for more than 20 years.
I'm skeptical. Also, Pfizer's vaccine needs to be stored at temperatures so low nobody has adequate equipment, and Moderna's just needs regular refrigeration. What's that about?
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| Posted 11/18/20 1:12 PM |
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Re: 2 covid-19 vaccines on the horizon
Posted by DancinBarefoot
Posted by GoldenRod
The fact that two separate companies came up with a similar answer, with similar results, speaks a lot for the vaccine.
I agree with this, but I can't help but be very concerned. First, just by the speed of all of this. It's way faster than any other vaccine has potentially come to market.
But also, 90%+ efficacy??? Really?? Flu vaccine is @ 60%. Two doses of MMR is @ 88% at protecting from mumps. Varicella is also in the 85-90% range. How is it that a brand new vaccine, for a novel virus, has such a high rate at protecting against contracting this illness?? Especially when all the studies and research have shown that contracting the illness doesn't appear to give sustained immunity as the antibodies diminish over time. Not to mention the fact that MMR and varicella have been distributed for more than 20 years.
I'm skeptical. Also, Pfizer's vaccine needs to be stored at temperatures so low nobody has adequate equipment, and Moderna's just needs regular refrigeration. What's that about?
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| Posted 11/18/20 1:14 PM |
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2 covid-19 vaccines on the horizon
If I’m not mistaken (which I could be), this has the potential to be successful bc it’s different from current vaccines. It targets mRNA, and doesn’t actually use a coronavirus. The vaccines we currently have trigger responses by injecting you with say, a small amount of measles.
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| Posted 11/18/20 1:28 AM |
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Re: 2 covid-19 vaccines on the horizon
Its just headlines, the rate is based on a small sample size of 100 people so I don't rely on headlines.
China already has come out with 4 vaccines, granted they are all in what we would deem Phase 3- but they had the genome sequence first and got a head start on formulating steps toward the vaccine. I also think we will hear more as time passes which one has the highest efficacy rate.
All these vaccine companies have published their up-to-date results in reputable medical journal Lancet to document and prove their vaccines. Thousands of shots have already been inoculated to frontline workers, military personnel, and essential people who must travel despite the Coronavirus. They have already administered the Sinopharm vaccine to the front-line healthcare workers and ambulance drivers in the United Arab Emirates. The Sheik of the UAE has also received it, to demonstrate how safe it is.
I also read that there was a virus outbreak in Huawei Mexico and none of the vaccinated employees tested positive while 10 of the 20 employees who didnt got Covid.
Message edited 11/18/2020 1:31:57 AM.
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| Posted 11/18/20 1:31 AM |
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GoldenRod
10 years on LIF!
Member since 11/06 26792 total posts
Name:
Shawn
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Re: 2 covid-19 vaccines on the horizon
Posted by DancinBarefoot
Posted by GoldenRod
The fact that two separate companies came up with a similar answer, with similar results, speaks a lot for the vaccine.
I agree with this, but I can't help but be very concerned. First, just by the speed of all of this. It's way faster than any other vaccine has potentially come to market.
But also, 90%+ efficacy??? Really?? Flu vaccine is @ 60%. Two doses of MMR is @ 88% at protecting from mumps. Varicella is also in the 85-90% range. How is it that a brand new vaccine, for a novel virus, has such a high rate at protecting against contracting this illness?? Especially when all the studies and research have shown that contracting the illness doesn't appear to give sustained immunity as the antibodies diminish over time. Not to mention the fact that MMR and varicella have been distributed for more than 20 years.
I'm skeptical. Also, Pfizer's vaccine needs to be stored at temperatures so low nobody has adequate equipment, and Moderna's just needs regular refrigeration. What's that about?
I've been reading bits and pieces about this. They've been working on this methodology of vaccine for several years. They just had to tweak it for this particular virus, so it's not as new as it sounds.
It's more efficient than most other vaccines because of the mRNA method they are using. It works completely differently than traditional vaccines.
Also, Covid-19 is relatively stable. It hasn't really mutated. Influenza mutates and shifts a lot, so it's hard to follow it.
I'm not sure about how long the immunity lasts, or why the temperature requirements are so different.
I'm not trying to convince anyone to take it. I'm still doing research myself on a lot of details.
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| Posted 11/18/20 1:39 AM |
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Sash
Peace
Member since 6/08 10312 total posts
Name:
fka LIW Smara
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Re: 2 covid-19 vaccines on the horizon
Awesome.. get this thing to market already.
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| Posted 11/18/20 1:42 AM |
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DancinBarefoot
06ers Rock!!
Member since 1/07 9534 total posts
Name:
The One My Mother Gave Me ;-)
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Re: 2 covid-19 vaccines on the horizon
Posted by GoldenRod
I'm not trying to convince anyone to take it. I'm still doing research myself on a lot of details.
I know. We're all in a boat trying to figure out the best way to navigate to the destination.
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| Posted 11/18/20 4:03 AM |
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seaside
LIF Adult
Member since 6/08 3101 total posts
Name:
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Re: 2 covid-19 vaccines on the horizon
Posted by GoldenRod
Posted by DancinBarefoot
Posted by GoldenRod
The fact that two separate companies came up with a similar answer, with similar results, speaks a lot for the vaccine.
I agree with this, but I can't help but be very concerned. First, just by the speed of all of this. It's way faster than any other vaccine has potentially come to market.
But also, 90%+ efficacy??? Really?? Flu vaccine is @ 60%. Two doses of MMR is @ 88% at protecting from mumps. Varicella is also in the 85-90% range. How is it that a brand new vaccine, for a novel virus, has such a high rate at protecting against contracting this illness?? Especially when all the studies and research have shown that contracting the illness doesn't appear to give sustained immunity as the antibodies diminish over time. Not to mention the fact that MMR and varicella have been distributed for more than 20 years.
I'm skeptical. Also, Pfizer's vaccine needs to be stored at temperatures so low nobody has adequate equipment, and Moderna's just needs regular refrigeration. What's that about?
I've been reading bits and pieces about this. They've been working on this methodology of vaccine for several years. They just had to tweak it for this particular virus, so it's not as new as it sounds.
It's more efficient than most other vaccines because of the mRNA method they are using. It works completely differently than traditional vaccines.
Also, Covid-19 is relatively stable. It hasn't really mutated. Influenza mutates and shifts a lot, so it's hard to follow it.
I'm not sure about how long the immunity lasts, or why the temperature requirements are so different.
I'm not trying to convince anyone to take it. I'm still doing research myself on a lot of details.
Was reading about some of this yesterday. What they have done is incredible. We are so lucky to live in this day and age....If the immunity lasts, this will definitely be a game-changer.
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| Posted 11/19/20 11:31 AM |
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