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Can you do PGD/PGS testing on frozen embies?

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08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

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Can you do PGD/PGS testing on frozen embies?

Our one fresh cycle, we did ICSI but didn't do PGD/PGS (BFP) and have 6 frozen embies. I don't know why but I feel like I want to test the remaining ones. Can that be done now? Thank you!

Message edited 4/11/2016 2:13:58 PM.

Posted 4/11/16 2:11 PM
 
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BabyBearA
LIF Adult

Member since 7/11

1254 total posts

Name:

Can you do PGD/PGS testing on frozen embies?

My doctor said this could be done ...

Posted 4/11/16 2:31 PM
 

IVFmiracle
Complete

Member since 12/12

4088 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

I can't imagine why not... I thought they only sent frozen embryos for PGD/PGS. Chat Icon

Message edited 4/11/2016 2:54:06 PM.

Posted 4/11/16 2:53 PM
 

PennyCat
Just call me mommy :)

Member since 7/08

19084 total posts

Name:
Jib

Re: Can you do PGD/PGS testing on frozen embies?

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.

Posted 4/11/16 3:23 PM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by BabyBearA

My doctor said this could be done ...



Thank you!!

Posted 4/11/16 3:28 PM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by IVFmiracle

I can't imagine why not... I thought they only sent frozen embryos for PGD/PGS. Chat Icon



I didn't know when it gets done.

Posted 4/11/16 3:29 PM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by PennyCat

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.




Ugh I don't like the sounds of this...

Posted 4/11/16 3:30 PM
 

PennyCat
Just call me mommy :)

Member since 7/08

19084 total posts

Name:
Jib

Re: Can you do PGD/PGS testing on frozen embies?

Posted by 08BabySurprise

Posted by PennyCat

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.




Ugh I don't like the sounds of this...



If you think about it, blinding putting back embryos vs putting back ones you know are genetically normal will HELP the chance of the embryo implanting, so perhaps in the end it all levels out-- but my biggest concern would be the lack of data on long term effects. It could be fine. I'd want more info.

Posted 4/11/16 3:33 PM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by PennyCat

Posted by 08BabySurprise

Posted by PennyCat

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.




Ugh I don't like the sounds of this...



If you think about it, blinding putting back embryos vs putting back ones you know are genetically normal will HELP the chance of the embryo implanting, so perhaps in the end it all levels out-- but my biggest concern would be the lack of data on long term effects. It could be fine. I'd want more info.



YOu make great points. Do you know anything about PGS? Assuming same thing has to happen? I'm just thinking ahead. Planning a FET in September or October so I haven't met with my RE yet. Plus I love getting "real" advice from the ladies here!

Posted 4/11/16 4:11 PM
 

aim
LIF Adult

Member since 4/11

1321 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by 08BabySurprise

Posted by IVFmiracle

I can't imagine why not... I thought they only sent frozen embryos for PGD/PGS. Chat Icon



I didn't know when it gets done.



The do not use frozen embryos. You do IVF. You decide if you are going to do PGS or PGD with a quick turn around to transfer right away. Or you decide to do the testing without the rush, freeze your embryos and do a FET later.

I did testing and chose to do FET just to give my body a break. My RE was happy as sometimes they need extra time to do the testing.

They biopsy the embryo 5 or 6 days old and then only freeze it if you are not doing a fresh transfer. At least that was what was done for me.

Message edited 4/11/2016 4:28:13 PM.

Posted 4/11/16 4:27 PM
 

aim
LIF Adult

Member since 4/11

1321 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by 08BabySurprise

Posted by PennyCat

Posted by 08BabySurprise

Posted by PennyCat

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.




Ugh I don't like the sounds of this...



If you think about it, blinding putting back embryos vs putting back ones you know are genetically normal will HELP the chance of the embryo implanting, so perhaps in the end it all levels out-- but my biggest concern would be the lack of data on long term effects. It could be fine. I'd want more info.



YOu make great points. Do you know anything about PGS? Assuming same thing has to happen? I'm just thinking ahead. Planning a FET in September or October so I haven't met with my RE yet. Plus I love getting "real" advice from the ladies here!

http://www.fertilitycenter.com/fertility_cares_blog/the-difference-between-pgd-and-pgs/

Posted 4/11/16 4:30 PM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by aim

Posted by 08BabySurprise

Posted by IVFmiracle

I can't imagine why not... I thought they only sent frozen embryos for PGD/PGS. Chat Icon



I didn't know when it gets done.



The do not use frozen embryos. You do IVF. You decide if you are going to do PGS or PGD with a quick turn around to transfer right away. Or you decide to do the testing without the rush, freeze your embryos and do a FET later.

I did testing and chose to do FET just to give my body a break. My RE was happy as sometimes they need extra time to do the testing.

They biopsy the embryo 5 or 6 days old and then only freeze it if you are not doing a fresh transfer. At least that was what was done for me.



Apparently they can do before a FET too from some little Googling that I did. I just need to research further and then ask my RE. Thank you!!! Chat Icon

Posted 4/11/16 4:40 PM
 

PennyCat
Just call me mommy :)

Member since 7/08

19084 total posts

Name:
Jib

Re: Can you do PGD/PGS testing on frozen embies?

Posted by 08BabySurprise

Posted by PennyCat

Posted by 08BabySurprise

Posted by PennyCat

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.




Ugh I don't like the sounds of this...



If you think about it, blinding putting back embryos vs putting back ones you know are genetically normal will HELP the chance of the embryo implanting, so perhaps in the end it all levels out-- but my biggest concern would be the lack of data on long term effects. It could be fine. I'd want more info.



YOu make great points. Do you know anything about PGS? Assuming same thing has to happen? I'm just thinking ahead. Planning a FET in September or October so I haven't met with my RE yet. Plus I love getting "real" advice from the ladies here!



I hear ya Chat Icon I did PGD on frozen embryos and CGH on a fresh cycle. PGD..,PGS...CGH... They all check for genetic abnormalities, the difference is the amount of information they provide. At least that's my understanding. Of course, you also get more info from a day 5 vs day 3, if you are fortunate enough to have embryos that make it to that stage.

We checked my frozen embryos when we were doing surrogacy because with all the money we were spending already, we wanted to be sure we were transferring back embryos that were genetically normal to take away any risk that it may not work- well- at least any risk we had control over! Since they were previously frozen at day 5, they were biopsied at that stage.

The fresh cycle where we did CGH, we tested at day 3 with the intention of doing a day 5 transfer. We put back 2 chromosomally normal embryos and while both took, we lost one at 7 weeks or so. I learned from that that it's NOT foolproof. However, since I had success with it, I'd do it again in the future. A little extra info can only helps.

Message edited 4/11/2016 7:49:57 PM.

Posted 4/11/16 7:48 PM
 

Hope2009
Thankful

Member since 1/09

4429 total posts

Name:
A

Can you do PGD/PGS testing on frozen embies?

What Jackie said. I did banking for what seemed like forever. Three cycles, freeze two and on the third i ended up with 12 embryos. Five of those made it to day five and PDG, aCGH. Out of those, two came back as normal. So yes, it can be done.

Posted 4/12/16 6:55 AM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by PennyCat

Posted by 08BabySurprise

Posted by PennyCat

Posted by 08BabySurprise

Posted by PennyCat

Yes, however, that means your frozen embryos will be thawed, biopsied, and frozen again, then thawed when you eventually decide to use them. The end result is it decreases the implantation rate. Also, I'd personally want to know the long term effects on a embryo that has gone through that much trauma. I don't think there's enough data on babies born under these circumstances. Ultimately though, it's a matter of weighing out the risks and benefits and then choosing what you're most comfortable with.




Ugh I don't like the sounds of this...



If you think about it, blinding putting back embryos vs putting back ones you know are genetically normal will HELP the chance of the embryo implanting, so perhaps in the end it all levels out-- but my biggest concern would be the lack of data on long term effects. It could be fine. I'd want more info.



YOu make great points. Do you know anything about PGS? Assuming same thing has to happen? I'm just thinking ahead. Planning a FET in September or October so I haven't met with my RE yet. Plus I love getting "real" advice from the ladies here!



I hear ya Chat Icon I did PGD on frozen embryos and CGH on a fresh cycle. PGD..,PGS...CGH... They all check for genetic abnormalities, the difference is the amount of information they provide. At least that's my understanding. Of course, you also get more info from a day 5 vs day 3, if you are fortunate enough to have embryos that make it to that stage.

We checked my frozen embryos when we were doing surrogacy because with all the money we were spending already, we wanted to be sure we were transferring back embryos that were genetically normal to take away any risk that it may not work- well- at least any risk we had control over! Since they were previously frozen at day 5, they were biopsied at that stage.

The fresh cycle where we did CGH, we tested at day 3 with the intention of doing a day 5 transfer. We put back 2 chromosomally normal embryos and while both took, we lost one at 7 weeks or so. I learned from that that it's NOT foolproof. However, since I had success with it, I'd do it again in the future. A little extra info can only helps.



THANK YOU FOR THIS!!!!!! Chat Icon Chat Icon Chat Icon Chat Icon

Posted 4/12/16 10:37 AM
 

aim
LIF Adult

Member since 4/11

1321 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by 08BabySurprise

Posted by aim

Posted by 08BabySurprise

Posted by IVFmiracle

I can't imagine why not... I thought they only sent frozen embryos for PGD/PGS. Chat Icon



I didn't know when it gets done.



The do not use frozen embryos. You do IVF. You decide if you are going to do PGS or PGD with a quick turn around to transfer right away. Or you decide to do the testing without the rush, freeze your embryos and do a FET later.

I did testing and chose to do FET just to give my body a break. My RE was happy as sometimes they need extra time to do the testing.

They biopsy the embryo 5 or 6 days old and then only freeze it if you are not doing a fresh transfer. At least that was what was done for me.



Apparently they can do before a FET too from some little Googling that I did. I just need to research further and then ask my RE. Thank you!!! Chat Icon



Cool!!! I had no idea. Best of luck!!Chat Icon

Posted 4/12/16 6:14 PM
 

08BabySurprise
My Life. My Everything.

Member since 10/07

9151 total posts

Name:

Re: Can you do PGD/PGS testing on frozen embies?

Posted by aim

Posted by 08BabySurprise

Posted by aim

Posted by 08BabySurprise

Posted by IVFmiracle

I can't imagine why not... I thought they only sent frozen embryos for PGD/PGS. Chat Icon



I didn't know when it gets done.



The do not use frozen embryos. You do IVF. You decide if you are going to do PGS or PGD with a quick turn around to transfer right away. Or you decide to do the testing without the rush, freeze your embryos and do a FET later.


I did testing and chose to do FET just to give my body a break. My RE was happy as sometimes they need extra time to do the testing.

They biopsy the embryo 5 or 6 days old and then only freeze it if you are not doing a fresh transfer. At least that was what was done for me.



Apparently they can do before a FET too from some little Googling that I did. I just need to research further and then ask my RE. Thank you!!! Chat Icon



Cool!!! I had no idea. Best of luck!!Chat Icon



THANK YOU!!! FINGERS CROSSED FOR YOU!!!!!!!! Chat Icon Chat Icon Chat Icon

Posted 4/13/16 12:08 PM
 
 

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